Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario
Clinical records of 222 patients with proven Crohn's disease identified at Queen's University Medical School in Kingston, Ontario from 1966 to 1984 were reviewed. Four clinical patterns were identified. Ileocolic disease (44%) was most trequent. Small intestinal involvement alone occurred...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1988-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1988/132031 |
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| Summary: | Clinical records of 222 patients with proven Crohn's disease identified
at Queen's University Medical School in Kingston, Ontario from 1966 to 1984 were
reviewed. Four clinical patterns were identified. Ileocolic disease (44%) was most
trequent. Small intestinal involvement alone occurred in 30% while colonic
involvement alone was documented in 18%. Gastroduodenal Crohn's disease was
diagnosed in 8.5%, but in all such patients there was involvement of additional small
or large bowel. Females (57%) out-numbered males (43%) with a female to male ratio
of 1.3. The age range at diagnosis was seven to 73 years and 177 patients (80%) were
diagnosed between the ages of 11 and 40 years. Patients with colonic disease only
tended to be older and had fewer obstructive episodes, fewer surgical resections and
more gross rectal bleeding. Patients with gascroduodenal disease were more often
male, usually had additional small bowel involvement, experienced more local
complications and required more surgical intervention than the ocher patterns. Only
one patient was identified with disease restricted to the anorectum. Patients in this
series were followed from two months to 24 years. The mean duration of follow-up
was 4.9 years. The frequency of complications and the necessity for surgery were
similar to other reported series. None of the patients had either large or small bowel
cancer during the follow-up period and there were no deaths related directly to
Crohn's disease, its complications or related surgery. |
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| ISSN: | 0835-7900 |