Chemical Assistance in Refolding of Bacterial Inclusion Bodies

Escherichia coli is one of the most widely used hosts for the production of recombinant proteins but insoluble expression of heterologous proteins is a major bottleneck in production of recombinant proteins in E. coli. In vitro refolding of inclusion body into proteins with native conformations is a...

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Bibliographic Details
Main Authors: Mona Alibolandi, Hasan Mirzahoseini
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2011/631607
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