Alterations in genes associated with cytosolic RNA sensing in whole blood are associated with coronary microvascular disease in SLE

Alterations in genes associated with cytosolic RNA sensing in whole blood are associated with coronary microvascular disease in SLE

Abstract Systemic lupus erythematosus (SLE) patients are 90% women and over three times more likely to die of cardiovascular disease than women in the general population. Chest pain with no obstructive cardiac disease is associated with coronary microvascular disease (CMD), where narrowing of the sm...

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Main Authors: Lihong Huo, Arati Naveen Kumar, Gantsetseg Tumurkhuu, Moumita Bose, Daniel S. Berman, Daniel J. Wallace, Janet Wei, Mariko Ishimori, C. Noel Bairey Merz, Caroline Jefferies
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Interferon
Coronary microvascular disease
Gene expression
Systemic lupus erythematosus
Online Access:https://doi.org/10.1038/s41598-024-82190-4
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https://doi.org/10.1038/s41598-024-82190-4

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