Applications of multiplexed CRISPR–Cas for genome engineering

Abstract The CRISPR–Cas system has become a worldwide genome editing tool for various organisms. Its precision and efficiency have facilitated basic research, drug discovery and therapeutic interventions. In contrast to other genome editing agents, CRISPR–Cas is modulated by a short guide RNA. Due t...

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Bibliographic Details
Main Authors: Himchan Cheng, Euihwan Jeong, Seung Woo Cho
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01500-6
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