Integrative proteomics and metabolomics reveal important pathways and potential biomarkers in high-altitude pulmonary hypertension

Integrative proteomics and metabolomics reveal important pathways and potential biomarkers in high-altitude pulmonary hypertension

Abstract High-altitude pulmonary hypertension (HAPH) is a severe condition affecting highland residents, yet its molecular mechanisms remain incompletely understood. This study aimed to investigate the pathogenesis of HAPH through integrated metabolomic and proteomic analyses. We performed untargete...

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Main Authors: Zhuo-ga Dan-zeng, Yang-jin Bai-ma, Ju Huang, Wang-jie Suo-lang, Qu-zhen Ge-sang, Yang-zong Suo-na, Yuan-sheng Wang, Zhuo-ga Baima, luo-bu Ge-sang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
High-altitude pulmonary hypertension
Proteomic
Metabolomic
Online Access:https://doi.org/10.1038/s41598-025-09477-y
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https://doi.org/10.1038/s41598-025-09477-y

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