Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion

Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion

Cryptococcus neoformans is an encapsulated yeast that causes disease mainly in immunosuppressed hosts. It is considered a facultative intracellular pathogen because of its capacity to survive and replicate inside phagocytes, especially macrophages. This ability is heavily dependent on various virule...

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Main Authors: Pedro Henrique Bürgel, Clara Luna Marina, Pedro H. V. Saavedra, Patrícia Albuquerque, Stephan Alberto Machado de Oliveira, Paulo Henrique de Holanda Veloso Janior, Raffael Araújo de Castro, Heino M. Heyman, Carolina Coelho, Radames J. B. Cordero, Arturo Casadevall, Joshua D. Nosanchuk, Ernesto S. Nakayasu, Robin C. May, Aldo Henrique Tavares, Anamelia Lorenzetti Bocca
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/3412763
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http://dx.doi.org/10.1155/2020/3412763

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