Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance

Among all solid tumors, the high-grade glioma appears to be the most vascularized one. In fact, “microvascular hyperplasia” is a hallmark of GBM. An altered vascular network determines irregular blood flow, so that tumor cells spread rapidly beyond the diffusion distance of oxygen in the tissue, wit...

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Bibliographic Details
Main Authors: Alessia Fidoamore, Loredana Cristiano, Andrea Antonosante, Michele d’Angelo, Erica Di Giacomo, Carlo Astarita, Antonio Giordano, Rodolfo Ippoliti, Elisabetta Benedetti, Annamaria Cimini
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/6809105
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