Association of the rs1800629 polymorphism in the TNF-α gene with nephrotic syndrome development: evidence from an updated meta-analysis

Abstract Introduction Despite its clinical significance, the precise pathogenesis of nephrotic syndrome (NS) remains elusive, with genetic factors and immune dysregulation implicated in disrupting glomerular filtration. Among these factors, TNF-α gene polymorphisms, such as the -308 G/A (rs1800629)...

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Bibliographic Details
Main Authors: Raphael Enrique Tiongco, Neil David Cayanan, Michael John Dominguez, Ma. Theresa Mae Doctora, Julie Ann Mercado
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Egyptian Pediatric Association Gazette
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Online Access:https://doi.org/10.1186/s43054-025-00396-1
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