Comparative Evaluation of Cyclooxygenase Inhibition Profiles Across Various NSAID Forms and Doses: Implications for Efficacy and Adverse Effects

Abstract Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain disorders and exert pharmacological effects by inhibiting cyclooxygenase (COX). Although previous studies have evaluated the COX inhibitory activity and selectivity of NSAIDs, none has compared COX inhibit...

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Bibliographic Details
Main Authors: Kenshu Shirakawa, Masafumi Takeno, Hidekazu Kuma, Takaaki Terahara, Shigeki Yamaguchi
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-12-01
Series:Pain and Therapy
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Online Access:https://doi.org/10.1007/s40122-024-00687-2
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