RNA modifications in cancer

RNA modifications in cancer

Abstract RNA modifications are emerging as critical cancer regulators that influence tumorigenesis and progression. Key modifications, such as N6‐methyladenosine (m6A) and 5‐methylcytosine (m5C), are implicated in various cellular processes. These modifications are regulated by proteins that write,...

Full description

Saved in:

Bibliographic Details
Main Authors:	Han Wu, Shi Chen, Xiang Li, Yuyang Li, He Shi, Yiwen Qing, Bohe Shi, Yifei Tang, Zhuoyi Yan, Yang Hao, Dongxu Wang, Weiwei Liu
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Series:	MedComm
Subjects:	cancer immune microenvironment immunotherapy programmed cell death RNA modifications
Online Access:	https://doi.org/10.1002/mco2.70042
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Editorial: Mechanism explorations of enhancing immunotherapeutic sensitivity via mediating immune infiltration and programmed cell death in solid tumor microenvironment
by: Fang Zheng, et al.
Published: (2025-01-01)

RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma
by: Qiang Xu, et al.
Published: (2025-01-01)

N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential
by: Qihui Wu, et al.
Published: (2025-01-01)

Harnessing nanoparticles for reshaping tumor immune microenvironment of hepatocellular carcinoma
by: JinSong Li, et al.
Published: (2025-02-01)

Immunotherapy in Recurrent Ovarian Cancer
by: Keyao Chen, et al.
Published: (2025-01-01)

Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment
by: Xiang Wang, et al.
Published: (2025-01-01)

RNA modifications: emerging players in the regulation of reproduction and development
by: Wen Junfei, et al.
Published: (2024-11-01)

Research Progress on Natural Products That Regulate miRNAs in the Treatment of Osteosarcoma
by: Lin Wang, et al.
Published: (2025-01-01)

Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis
by: Xinyan Hao, et al.
Published: (2025-01-01)

Pre-injection of exosomes can significantly suppress ovarian cancer growth by activating the immune system in mice
by: Yuanyuan Wang, et al.
Published: (2025-02-01)

Epigenetic Regulation of Stromal and Immune Cells and Therapeutic Targets in the Tumor Microenvironment
by: Kang Liu, et al.
Published: (2025-01-01)

Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy
by: Yonghua Cai, et al.
Published: (2025-02-01)

Exploring RNA modifications in infectious non-coding circular RNAs
by: Pavel Vopalensky, et al.
Published: (2025-02-01)

Macrophages facilitate tumor cell PD‐L1 expression via an IL‐1β‐centered loop to attenuate immune checkpoint blockade
by: Cheng Xu, et al.
Published: (2023-04-01)

Multi-omic and machine learning analysis of mitochondrial RNA modification genes in lung adenocarcinoma for prognostic and therapeutic implications
by: Xiao Zhang, et al.
Published: (2025-03-01)

The Immune Landscape and Its Potential for Immunotherapy in Advanced Biliary Tract Cancer
by: Andry Santoso, et al.
Published: (2024-12-01)

Immunotherapy of osteosarcoma based on immune microenvironment modulation
by: Heping Lian, et al.
Published: (2025-01-01)

Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms
by: Jiali Yao, et al.
Published: (2025-01-01)

Bioinformatic characterization of STING expression in hematological malignancies reveals association with prognosis and anti-tumor immunity
by: Xiang-mei Wen, et al.
Published: (2025-02-01)

“Tumor immunology meets oncology” (TIMO), 18 April–20 April 2024, in Brandenburg an der Havel, Germany
by: Barbara Seliger
Published: (2024-11-01)

RNA N4‐acetylcytidine modification and its role in health and diseases
by: Qiang Wang, et al.
Published: (2025-01-01)

Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges
by: Man Wang, et al.
Published: (2025-01-01)

Examining the Gm18 and mG Modification Positions in tRNA Sequences
by: Mayavan Subramanian, et al.
Published: (2014-06-01)

A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA
by: Guojuan Sun, et al.
Published: (2025-01-01)

The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy
by: Qinglong Ma, et al.
Published: (2025-01-01)

Novel protein-based prognostic signature linked to immunotherapeutic efficiency in ovarian cancer
by: Shuo-Fu Chen, et al.
Published: (2024-09-01)

Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer
by: Yuanyuan Wang, et al.
Published: (2025-02-01)

Neoantigen mRNA vaccines and A2A receptor antagonism: A strategy to enhance T cell immunity
by: Saber Imani, et al.
Published: (2025-12-01)

TLR7: A Key Prognostic Biomarker and Immunotherapeutic Target in Lung Adenocarcinoma
by: Feiming Hu, et al.
Published: (2025-01-01)

An anoikis-related signature predicts prognosis and immunotherapy response in gastrointestinal cancers
by: Ruyi Liu, et al.
Published: (2025-02-01)

Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data
by: Zhou J, et al.
Published: (2025-01-01)

Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and bulk RNA-seq
by: Yulin Shi, et al.
Published: (2025-02-01)

New insights into N6-methyladenosine in hepatocellular carcinoma immunotherapy
by: Mengran Li, et al.
Published: (2025-01-01)

Multiple programmed cell death patterns predict the prognosis and drug sensitivity in gastric cancer
by: Qiying Song, et al.
Published: (2025-02-01)

Predicting immunotherapy efficacy in endometrial cancer: focus on the tumor microenvironment
by: Liubov A. Tashireva, et al.
Published: (2025-01-01)

Research progress of HIF-1a on immunotherapy outcomes in immune vascular microenvironment
by: Shaoyan Shi, et al.
Published: (2025-02-01)

Reversing NK cell exhaustion: a novel strategy combining immune checkpoint blockade with drug sensitivity enhancement in the treatment of hepatocellular carcinoma
by: Yuxiang Huang, et al.
Published: (2025-01-01)

Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer
by: Yuqi Wang, et al.
Published: (2025-01-01)

Adeno-associated virus mediated artificial circular RNA for triggering cancer immunotherapy to treat prostate cancer
by: Chujin Ye, et al.
Published: (2025-01-01)

Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs
by: Wei Li, et al.
Published: (2025-02-01)