Definitions, measurement, and reporting of progression-free survival in randomized clinical trials and observational studies of patients with advanced non-small-cell lung cancer treated with immunotherapy: a scoping review

Definitions, measurement, and reporting of progression-free survival in randomized clinical trials and observational studies of patients with advanced non-small-cell lung cancer treated with immunotherapy: a scoping review

Background: Evidence from observational studies is increasingly used in oncology to complement evidence from clinical trials. Commonly used endpoints to evaluate oncology medicines are overall survival (OS) and progression-free survival (PFS). However, comparing PFS across observational studies and...

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Main Authors: M.V. Verschueren, V.P. Tassopoulou, R. Visscher, J. Schuurkamp, B.J.M. Peters, M. Koopman, E.M.W. van de Garde, A.C.G. Egberts, L.T. Bloem
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:ESMO Real World Data and Digital Oncology
Subjects:
progression-free survival
observational studies
randomized clinical trials
advanced non-small-cell lung cancer
immunotherapy
scoping review
Online Access:http://www.sciencedirect.com/science/article/pii/S2949820125000074
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