Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review

Introduction. Heterotopic pancreas (HP) is the congenital presence of pancreatic tissue outside its normal location in the absence of vascular and anatomical connection with the main pancreas. HP can affect any part of the gastrointestinal tract, and it is mostly encountered in the stomach. The gall...

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Main Authors: Emad Aborajooh, Ibrahim Khalil Khairi Ghayada, Yasser Mustafa Issa Lafi
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2021/6611291
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author Emad Aborajooh
Ibrahim Khalil Khairi Ghayada
Yasser Mustafa Issa Lafi
author_facet Emad Aborajooh
Ibrahim Khalil Khairi Ghayada
Yasser Mustafa Issa Lafi
author_sort Emad Aborajooh
collection DOAJ
description Introduction. Heterotopic pancreas (HP) is the congenital presence of pancreatic tissue outside its normal location in the absence of vascular and anatomical connection with the main pancreas. HP can affect any part of the gastrointestinal tract, and it is mostly encountered in the stomach. The gallbladder is a rare site of HP, and our literature review revealed that only 38 cases were reported. We present a case of HP in the gallbladder that was presented with a picture of acute cholecystitis. After the case presentation, we will discuss HP in the gallbladder by reviewing the literature. Case Presentation. A 49-year-old male presented to the emergency department complaining of progressively worsening right upper abdominal pain for the last 24 hours. After thorough history and physical examination, a provisional diagnosis of acute cholecystitis was made. Abdominal ultrasonography revealed a rim of edema surrounding the gallbladder wall with two stones impacted at the gallbladder neck. Laparoscopic cholecystectomy was performed with an uneventful postoperative course, and the patient was discharged the next day. Microscopic examination of the gallbladder showed that a heterotopic pancreatic tissue, composed of a large number of pancreatic acini and few ducts with the absence of islets of Langerhans, was found around the cystic duct. The patient was asymptomatic at the regular follow-up six months postoperatively. Conclusion. HP in the gallbladder is an extremely rare finding. Its clinical presentation is not different from other cholecystopathic diseases. Most cases were accompanied by cholelithiasis. Preoperative laboratory and imaging modalities are usually not helpful in the diagnosis of HP in the gallbladder. The definitive diagnosis is made by histological examination of the gallbladder specimen. Laparoscopic cholecystectomy is sufficing treatment.
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spelling doaj-art-28c038ce4c5546d1824d18eaa3caa5af2025-02-03T01:03:58ZengWileyCase Reports in Medicine1687-96271687-96352021-01-01202110.1155/2021/66112916611291Heterotopic Pancreas in the Gallbladder: Case Report and Literature ReviewEmad Aborajooh0Ibrahim Khalil Khairi Ghayada1Yasser Mustafa Issa Lafi2Department of Surgery and Anaesthesia, Faculty of Medicine, Mutah University, Kerak, JordanDepartment of Medicine, Al-Basheer Hospital, Amman, JordanDepartment of Medicine, Al-Basheer Hospital, Amman, JordanIntroduction. Heterotopic pancreas (HP) is the congenital presence of pancreatic tissue outside its normal location in the absence of vascular and anatomical connection with the main pancreas. HP can affect any part of the gastrointestinal tract, and it is mostly encountered in the stomach. The gallbladder is a rare site of HP, and our literature review revealed that only 38 cases were reported. We present a case of HP in the gallbladder that was presented with a picture of acute cholecystitis. After the case presentation, we will discuss HP in the gallbladder by reviewing the literature. Case Presentation. A 49-year-old male presented to the emergency department complaining of progressively worsening right upper abdominal pain for the last 24 hours. After thorough history and physical examination, a provisional diagnosis of acute cholecystitis was made. Abdominal ultrasonography revealed a rim of edema surrounding the gallbladder wall with two stones impacted at the gallbladder neck. Laparoscopic cholecystectomy was performed with an uneventful postoperative course, and the patient was discharged the next day. Microscopic examination of the gallbladder showed that a heterotopic pancreatic tissue, composed of a large number of pancreatic acini and few ducts with the absence of islets of Langerhans, was found around the cystic duct. The patient was asymptomatic at the regular follow-up six months postoperatively. Conclusion. HP in the gallbladder is an extremely rare finding. Its clinical presentation is not different from other cholecystopathic diseases. Most cases were accompanied by cholelithiasis. Preoperative laboratory and imaging modalities are usually not helpful in the diagnosis of HP in the gallbladder. The definitive diagnosis is made by histological examination of the gallbladder specimen. Laparoscopic cholecystectomy is sufficing treatment.http://dx.doi.org/10.1155/2021/6611291
spellingShingle Emad Aborajooh
Ibrahim Khalil Khairi Ghayada
Yasser Mustafa Issa Lafi
Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review
Case Reports in Medicine
title Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review
title_full Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review
title_fullStr Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review
title_full_unstemmed Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review
title_short Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review
title_sort heterotopic pancreas in the gallbladder case report and literature review
url http://dx.doi.org/10.1155/2021/6611291
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AT ibrahimkhalilkhairighayada heterotopicpancreasinthegallbladdercasereportandliteraturereview
AT yassermustafaissalafi heterotopicpancreasinthegallbladdercasereportandliteraturereview