Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance
This study is aimed at investigating probable disruption of the metastable balance relevant to a disruption of the mental processes observed in the neurophenomenal level. This disruption was found to occur under dense auditory verbal hallucinations (AVHs) which are accompanied by thought blocking (T...
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Wiley
2018-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2018/4031207 |
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| author | Elias Koutsoukos Elias Angelopoulos |
| author_facet | Elias Koutsoukos Elias Angelopoulos |
| author_sort | Elias Koutsoukos |
| collection | DOAJ |
| description | This study is aimed at investigating probable disruption of the metastable balance relevant to a disruption of the mental processes observed in the neurophenomenal level. This disruption was found to occur under dense auditory verbal hallucinations (AVHs) which are accompanied by thought blocking (TB) phenomena. The entropy that quantifies the complexity of the spontaneous coupling has been used to describe the observed transitions. According to our findings, the high synchrony-derived entropy (SE) defines a metastable state, where formations of cortical areas are able to coordinate transiently under the demands of stimulus-oriented processes or other internal cognitive associations. It was also found that the disruption of the sensitive balance to the side of oversynergy (overconnectedness) rather than the side of independence (coincidental coupling) is relevant with functional fixations under the specific symptom of schizophrenia. An introduced measure relative to the persistence of coupling indicated that the overcoupled brain areas exhibit a kind of “stiffness” in processing incoherent phasic components. Our consideration enhances the understanding of the role the metastability plays in the interpretation of deeply subjective phenomena, such as AVHs and TBs that affect the normal information routing in the brain. |
| format | Article |
| id | doaj-art-28b989036315415facd0c95b10a897b3 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-28b989036315415facd0c95b10a897b32025-02-03T05:52:50ZengWileyBehavioural Neurology0953-41801875-85842018-01-01201810.1155/2018/40312074031207Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable BalanceElias Koutsoukos0Elias Angelopoulos1Medical School, 1st Psychiatric Department, Eginition Hospital, Athens University, 72-74 Vas. Sofias Ave., 115 28 Athens, GreeceMedical School, 1st Psychiatric Department, Eginition Hospital, Athens University, 72-74 Vas. Sofias Ave., 115 28 Athens, GreeceThis study is aimed at investigating probable disruption of the metastable balance relevant to a disruption of the mental processes observed in the neurophenomenal level. This disruption was found to occur under dense auditory verbal hallucinations (AVHs) which are accompanied by thought blocking (TB) phenomena. The entropy that quantifies the complexity of the spontaneous coupling has been used to describe the observed transitions. According to our findings, the high synchrony-derived entropy (SE) defines a metastable state, where formations of cortical areas are able to coordinate transiently under the demands of stimulus-oriented processes or other internal cognitive associations. It was also found that the disruption of the sensitive balance to the side of oversynergy (overconnectedness) rather than the side of independence (coincidental coupling) is relevant with functional fixations under the specific symptom of schizophrenia. An introduced measure relative to the persistence of coupling indicated that the overcoupled brain areas exhibit a kind of “stiffness” in processing incoherent phasic components. Our consideration enhances the understanding of the role the metastability plays in the interpretation of deeply subjective phenomena, such as AVHs and TBs that affect the normal information routing in the brain.http://dx.doi.org/10.1155/2018/4031207 |
| spellingShingle | Elias Koutsoukos Elias Angelopoulos Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance Behavioural Neurology |
| title | Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance |
| title_full | Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance |
| title_fullStr | Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance |
| title_full_unstemmed | Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance |
| title_short | Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance |
| title_sort | indication of disrupted temporal structure in the case of thought blocks in schizophrenia the role of the metastable balance |
| url | http://dx.doi.org/10.1155/2018/4031207 |
| work_keys_str_mv | AT eliaskoutsoukos indicationofdisruptedtemporalstructureinthecaseofthoughtblocksinschizophreniatheroleofthemetastablebalance AT eliasangelopoulos indicationofdisruptedtemporalstructureinthecaseofthoughtblocksinschizophreniatheroleofthemetastablebalance |