An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH

ABSTRACT The mechanisms controlling Mycobacterium tuberculosis (Mtb) replication and survival inside its human host remain ill-defined. Phagosome acidification and nutrient deprivation are common mechanisms used by macrophages to restrict the replication of intracellular bacteria. Mtb stops replicat...

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Bibliographic Details
Main Authors: Claire Healy, Sabine Ehrt, Alexandre Gouzy
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02825-24
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