Characteristics and clinical significance of immune cells in omental milky spots of patients with gastric cancer

Characteristics and clinical significance of immune cells in omental milky spots of patients with gastric cancer

The omentum is a common site of peritoneal metastasis in various cancers, including gastric cancer. It contains immune cell aggregates known as milky spots, which provide a microenvironment for peritoneal immunity by regulating innate and adaptive immune responses. In this study, we investigated gen...

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Bibliographic Details
Main Authors: Yasunobu Mano, Yuka Igarashi, Keisuke Komori, Itaru Hashimoto, Hayato Watanabe, Kosuke Takahashi, Kazuki Kano, Hirohito Fujikawa, Takanobu Yamada, Hidetomo Himuro, Taku Kouro, Feifei Wei, Kayoko Tsuji, Shun Horaguchi, Mitsuru Komahashi, Takashi Oshima, Tetsuro Sasada
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
omental milky spots
gastric cancer
adaptive immune responses
lymphatic invasion
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1521278/full
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