Study of the <i>MTHFR</i> 677C>T Polymorphism in Children and Adolescents with Hashimoto’s Thyroiditis: An Original Case–Control Study

Study of the <i>MTHFR</i> 677C>T Polymorphism in Children and Adolescents with Hashimoto’s Thyroiditis: An Original Case–Control Study

<b>Background/Objectives</b>: Hashimoto’s thyroiditis (HT) is the most common cause of hypothyroidism during childhood and adolescence. Children and adolescents with HT have an increased susceptibility to the development of thyroid nodules and thyroid cancer. Among the genetic causes of...

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Main Authors: Savvas Kolanis, Elisavet Georgiou, Eleni P. Kotanidou, Vasiliki Rengina Tsinopoulou, Evdoxia Sapountzi, Emmanouel Hatzipantelis, Liana Fidani, Assimina Galli-Tsinopoulou
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diagnostics
Subjects:
Hashimoto thyroiditis
methylenetetrahydrofolate reductase
<i>MTHFR</i> gene
single nucleotide polymorphism
anti-TPO
anti-TG
Online Access:https://www.mdpi.com/2075-4418/15/11/1310
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