ISCAZIM: Integrated statistical correlation analysis for zero-inflated microbiome data

Microbiome-metabolome association analysis is critical to reveal the key pairs of gut microbiota and metabolites for discovery of the microbial biomarkers in chronic diseases. However, the characteristics of microbiome data, such as zero inflation, over dispersion, may impair the confidence of assoc...

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Bibliographic Details
Main Authors: Zhe Fan, Jiali Lv, Shuai Zhang, Bingbing Gu, Cheng Wang, Tao Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024172155
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