4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery
Abstract With precise control of smart materials deformation in time dimension, doctors can customize orthopedic implants. This review focuses on the advances of 4D printing technology in orthopedics, including its applications in bone repair and reconstruction, personalized treatment, and drug deli...
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| Format: | Article |
| Language: | English |
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BMC
2025-01-01
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| Series: | BioMedical Engineering OnLine |
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| Online Access: | https://doi.org/10.1186/s12938-025-01334-3 |
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| _version_ | 1832585480261074944 |
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| author | Chenxi Shen Aiyong Shen |
| author_facet | Chenxi Shen Aiyong Shen |
| author_sort | Chenxi Shen |
| collection | DOAJ |
| description | Abstract With precise control of smart materials deformation in time dimension, doctors can customize orthopedic implants. This review focuses on the advances of 4D printing technology in orthopedics, including its applications in bone repair and reconstruction, personalized treatment, and drug delivery. 4D printing enables the creation of bionic scaffolds and fixation devices for bone repair, customized implants matching patients' conditions for personalized treatment, and specific carriers for accurate drug release and delivery, which together contribute to accelerating bone healing, providing exclusive treatments, enhancing therapeutic effects and reducing side effects, thus helping improve orthopedic medicine. It offers comprehensive reference materials for relevant medical personnel. |
| format | Article |
| id | doaj-art-280efa6619b845008a5ea6c4a77d74f7 |
| institution | Kabale University |
| issn | 1475-925X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BioMedical Engineering OnLine |
| spelling | doaj-art-280efa6619b845008a5ea6c4a77d74f72025-01-26T12:44:58ZengBMCBioMedical Engineering OnLine1475-925X2025-01-0124112110.1186/s12938-025-01334-34D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug deliveryChenxi Shen0Aiyong Shen1Chongqing Medical UniversityThe Fourth People’s Hospital of Wujiang DistrictAbstract With precise control of smart materials deformation in time dimension, doctors can customize orthopedic implants. This review focuses on the advances of 4D printing technology in orthopedics, including its applications in bone repair and reconstruction, personalized treatment, and drug delivery. 4D printing enables the creation of bionic scaffolds and fixation devices for bone repair, customized implants matching patients' conditions for personalized treatment, and specific carriers for accurate drug release and delivery, which together contribute to accelerating bone healing, providing exclusive treatments, enhancing therapeutic effects and reducing side effects, thus helping improve orthopedic medicine. It offers comprehensive reference materials for relevant medical personnel.https://doi.org/10.1186/s12938-025-01334-34D printingBone repair and reconstructionPersonalized orthopedic treatmentDrug delivery |
| spellingShingle | Chenxi Shen Aiyong Shen 4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery BioMedical Engineering OnLine 4D printing Bone repair and reconstruction Personalized orthopedic treatment Drug delivery |
| title | 4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery |
| title_full | 4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery |
| title_fullStr | 4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery |
| title_full_unstemmed | 4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery |
| title_short | 4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery |
| title_sort | 4d printing innovative solutions and technological advances in orthopedic repair and reconstruction personalized treatment and drug delivery |
| topic | 4D printing Bone repair and reconstruction Personalized orthopedic treatment Drug delivery |
| url | https://doi.org/10.1186/s12938-025-01334-3 |
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