FNDC3B promotes gastric cancer metastasis via interacting with FAM83H and preventing its proteasomal degradation

FNDC3B promotes gastric cancer metastasis via interacting with FAM83H and preventing its proteasomal degradation

Abstract Background Gastric cancer (GC) is one of the most prevalent digestive tract malignancies, with metastasis being a major contributor to poor prognosis in patients. Fibronectin type III domain-containing 3B (FNDC3B) plays pivotal roles in various tumors, yet its role in GC remains unknown. Me...

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Main Authors: Yuying Zhang, Lingyu Ran, Yuying Liu, Wei Li, Ai Ran, Haiping Li, Bo Huang, Junwu Ren, Hao Ning, Qiang Ma, Xiaolin Wang, Feifei Yang, Xiaojuan Pan, Ce Liang, Shimin Wang, Changhong Qin, Yan Jiang, Kun Qian, Bin Xiao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
FNDC3B
FAM83H
Proteasomal degradation
TM domain
GC
Online Access:https://doi.org/10.1186/s11658-025-00741-7
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https://doi.org/10.1186/s11658-025-00741-7

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