Abundance of a metabolically active subpopulation in dedifferentiated adipocytes inversely correlates with body mass index

Abundance of a metabolically active subpopulation in dedifferentiated adipocytes inversely correlates with body mass index

Objective: The cellular composition and functionality of adipose tissue are key determinants of metabolic diseases associated with adipose tissue dysregulation, such as obesity. We hypothesized that distinct subpopulations with unique gene expression profiles and functional characteristics exist wit...

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Bibliographic Details
Main Authors: Jonathan Trujillo-Viera, Mona C. Wittmann, Daniel Lam, Yang Shen, Adhideb Ghosh, Falko Noé, Anne Hoffmann, Coralie Viollet, Alec Dick, Matthias Blüher, Jiawei Zhong, Lucas Massier, Christian Wolfrum, Holger Klein, Heike Neubauer, Bradford Hamilton
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Molecular Metabolism
Subjects:
Energy expenditure
DFAT
Adipocytes
Obesity
CD36
CD146
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000687
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