Roasted <i>Astragalus membranaceus</i> Inhibits Aβ25–35-Induced Oxidative Stress in Neuronal Cells by Activating the Nrf2/HO-1 and AKT/CREB/BDNF Pathways

Roasted <i>Astragalus membranaceus</i> Inhibits Aβ25–35-Induced Oxidative Stress in Neuronal Cells by Activating the Nrf2/HO-1 and AKT/CREB/BDNF Pathways

(1) Background: <i>Astragalus membranaceus</i> (AM) has antioxidant and anti-inflammatory effects, but its specific mechanism of action in the brain is still unclear. In this study, we developed a roasting process to maximize the cognitive improvement impact of AM. We focused on enhancin...

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Bibliographic Details
Main Authors: Yun-Jeong Ji, Min Hye Kang, Sin Hee Han, Geum-Soog Kim, Hyung Don Kim, Gwi Yeong Jang
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antioxidants
Subjects:
<i>Astragalus membranaceus</i>
Alzheimer’s disease
BDNF pathways
hippocampal neuronal cells
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/13/11/1311
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https://www.mdpi.com/2076-3921/13/11/1311

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