MicroRNA-155 modulates methotrexate-induced spatial memory impairment by disruption of the blood-brain barrier integrity
Aim: Methotrexate (MTX) is a commonly used chemotherapy drug, yet its late neurotoxic side effects are gaining attention. The aim of the study was to evaluate the role of miR-155 in the pathogenesis of MTX-induced cognitive impairment, mainly focused on the interplay of blood-brain barrier (BBB) int...
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Main Authors: | Yu-Chieh Chen, Li-Tung Huang, Hong-Ren Yu, Jiunn-Ming Sheen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
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Series: | Brain Research Bulletin |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923025000528 |
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