Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase
Background Patients with severe coronavirus disease 2019 (COVID-19) have been reported to show hypoxia without displaying typical clinical signs or symptoms, called “happy hypoxia.” To explore the potential of happy hypoxia as a distinctive symptom of COVID-19, we compared vital signs in the triage...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Future Science OA |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/20565623.2025.2458413 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832578776737775616 |
|---|---|
| author | Mihiro Kaga Masanao Sasaki Takahiro Masuda Hiroyuki Sato Takeshi Ueda Akihiro Hirakawa |
| author_facet | Mihiro Kaga Masanao Sasaki Takahiro Masuda Hiroyuki Sato Takeshi Ueda Akihiro Hirakawa |
| author_sort | Mihiro Kaga |
| collection | DOAJ |
| description | Background Patients with severe coronavirus disease 2019 (COVID-19) have been reported to show hypoxia without displaying typical clinical signs or symptoms, called “happy hypoxia.” To explore the potential of happy hypoxia as a distinctive symptom of COVID-19, we compared vital signs in the triage phase between patients with and without COVID-19.Methods We retrospectively identified emergency patients with and without COVID-19 admitted to Rakuwakai Marutamachi Hospital, Kyoto, Japan, between January 2021 and December 2021.Results and Conclusions 317 patients were analyzed. Multivariate logistic regression analysis, including all vital signs, demonstrated that the respiratory rate was not statistically associated with COVID-19 (odds ratio, 0.94, p = 0.058), suggesting that happy hypoxia may not be a distinct hallmark of COVID-19. |
| format | Article |
| id | doaj-art-275cf9d67d4e476babda091b3eeb22f6 |
| institution | Kabale University |
| issn | 2056-5623 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-275cf9d67d4e476babda091b3eeb22f62025-01-30T13:37:53ZengTaylor & Francis GroupFuture Science OA2056-56232025-12-0111110.1080/20565623.2025.2458413Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phaseMihiro Kaga0Masanao Sasaki1Takahiro Masuda2Hiroyuki Sato3Takeshi Ueda4Akihiro Hirakawa5Department of Clinical Biostatistics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, JapanDepartment of Clinical Biostatistics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, JapanDepartment of Clinical Biostatistics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, JapanDepartment of Clinical Biostatistics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, JapanEmergency and General Internal Medicine, Rakuwakai Marutamachi Hospital, Kyoto, JapanDepartment of Clinical Biostatistics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, JapanBackground Patients with severe coronavirus disease 2019 (COVID-19) have been reported to show hypoxia without displaying typical clinical signs or symptoms, called “happy hypoxia.” To explore the potential of happy hypoxia as a distinctive symptom of COVID-19, we compared vital signs in the triage phase between patients with and without COVID-19.Methods We retrospectively identified emergency patients with and without COVID-19 admitted to Rakuwakai Marutamachi Hospital, Kyoto, Japan, between January 2021 and December 2021.Results and Conclusions 317 patients were analyzed. Multivariate logistic regression analysis, including all vital signs, demonstrated that the respiratory rate was not statistically associated with COVID-19 (odds ratio, 0.94, p = 0.058), suggesting that happy hypoxia may not be a distinct hallmark of COVID-19.https://www.tandfonline.com/doi/10.1080/20565623.2025.2458413COVID-19hypoxiarespiratory ratetriagevital signs |
| spellingShingle | Mihiro Kaga Masanao Sasaki Takahiro Masuda Hiroyuki Sato Takeshi Ueda Akihiro Hirakawa Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase Future Science OA COVID-19 hypoxia respiratory rate triage vital signs |
| title | Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase |
| title_full | Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase |
| title_fullStr | Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase |
| title_full_unstemmed | Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase |
| title_short | Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase |
| title_sort | exploring the association between happy hypoxia and coronavirus disease 2019 in the triage phase |
| topic | COVID-19 hypoxia respiratory rate triage vital signs |
| url | https://www.tandfonline.com/doi/10.1080/20565623.2025.2458413 |
| work_keys_str_mv | AT mihirokaga exploringtheassociationbetweenhappyhypoxiaandcoronavirusdisease2019inthetriagephase AT masanaosasaki exploringtheassociationbetweenhappyhypoxiaandcoronavirusdisease2019inthetriagephase AT takahiromasuda exploringtheassociationbetweenhappyhypoxiaandcoronavirusdisease2019inthetriagephase AT hiroyukisato exploringtheassociationbetweenhappyhypoxiaandcoronavirusdisease2019inthetriagephase AT takeshiueda exploringtheassociationbetweenhappyhypoxiaandcoronavirusdisease2019inthetriagephase AT akihirohirakawa exploringtheassociationbetweenhappyhypoxiaandcoronavirusdisease2019inthetriagephase |