The Deletion of the MGF360-10L/505-7R Genes of African Swine Fever Virus Results in High Attenuation but No Protection Against Homologous Challenge in Pigs

The Deletion of the MGF360-10L/505-7R Genes of African Swine Fever Virus Results in High Attenuation but No Protection Against Homologous Challenge in Pigs

African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), a severe hemorrhagic disease with a mortality rate reaching 100%. Despite extensive research on ASFV mechanisms, no safe and effective vaccines or antiviral treatments have been developed. Live attenuated vaccines...

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Bibliographic Details
Main Authors: Linlin Zheng, Zilong Yan, Xiaolan Qi, Jingjing Ren, Zhao Ma, Huanan Liu, Zhao Zhang, Dan Li, Jingjing Pei, Shuqi Xiao, Tao Feng, Xinglong Wang, Haixue Zheng
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Viruses
Subjects:
ASFV
MGF360-10L
MGF505-7R
attenuated strain
immunoprotection
Online Access:https://www.mdpi.com/1999-4915/17/2/283
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