Stretching and immobilizing a single DNA molecule on a glass surface using pressure flow in a microchannel for super-resolution imaging

Single-DNA analysis combines fluorescence microscopy with a method of stretching a single DNA molecule from its random coil shape to a linear shape. Although super-resolution imaging methods can be used for analyzing the DNA with a higher lateral resolution, these methods require several seconds to...

Full description

Saved in:
Bibliographic Details
Main Authors: Naoki Azuma, Ryotaro Suzuki, Kenji Fukuzawa, Shintaro Itoh, Hedong Zhang
Format: Article
Language:English
Published: AIP Publishing LLC 2025-01-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/5.0223375
Tags: Add Tag
No Tags, Be the first to tag this record!