Elucidating tobacco smoke-induced craniofacial deformities: Biomarker and MAPK signaling dysregulation unraveled by cross-species multi-omics analysis

Elucidating tobacco smoke-induced craniofacial deformities: Biomarker and MAPK signaling dysregulation unraveled by cross-species multi-omics analysis

Tobacco smoke (TS), particularly secondhand and thirdhand smoke, poses a pervasive and intractable environmental hazard that promotes teratogenesis and the progression of craniofacial malformations, although the underlying mechanisms remain elusive. Using zebrafish larvae as a model, our research de...

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Bibliographic Details
Main Authors: Yuxin Lin, Hao Li, Shukai Zheng, Rui Han, Kusheng Wu, Shijie Tang, Xiaoping Zhong, Jiasheng Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Tobacco smoke
Craniofacial development
The MAPK signaling pathway
MiRNAs
Cross-species multi-omics analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324014192
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