Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report
This case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman. This exophytic, multicystic, 6.5 × 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2012/793963 |
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| _version_ | 1832554206274256896 |
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| author | N. Thao T. Nguyen Theresa R. Harring Laurie Holley John A. Goss Christine A. O’Mahony |
| author_facet | N. Thao T. Nguyen Theresa R. Harring Laurie Holley John A. Goss Christine A. O’Mahony |
| author_sort | N. Thao T. Nguyen |
| collection | DOAJ |
| description | This case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman. This exophytic, multicystic, 6.5 × 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma. This is the seventh case described in the literature. Multiple foci of high-grade dysplasia/carcinoma in situ were found with a microscopic focus of invasive carcinoma in review of the pathology, making this only the second case reporting malignant transformation. It is presented to illustrate the premalignant potential in a biliary epithelial tumor currently categorized as benign. |
| format | Article |
| id | doaj-art-25b990cfe84d470c92bc80db04c0dc72 |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-25b990cfe84d470c92bc80db04c0dc722025-02-03T05:52:02ZengWileyCase Reports in Hepatology2090-65872090-65952012-01-01201210.1155/2012/793963793963Biliary Adenofibroma with Carcinoma In Situ: A Rare Case ReportN. Thao T. Nguyen0Theresa R. Harring1Laurie Holley2John A. Goss3Christine A. O’Mahony4Department of Surgery, Baylor College of Medicine, One Baylor Plaza, Suite 404D, Houston, TX 77030, USADepartment of Surgery, Baylor College of Medicine, One Baylor Plaza, Suite 404D, Houston, TX 77030, USADepartment of Pathology, St. Luke’s Episcopal Hospital, 6720 Bertner Avenue, Houston, TX 77030, USADivision of Abdominal Transplantation, Baylor College of Medicine, One Baylor Plaza, Suite 404D, Houston, TX 77030, USADivision of Abdominal Transplantation, Baylor College of Medicine, One Baylor Plaza, Suite 404D, Houston, TX 77030, USAThis case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman. This exophytic, multicystic, 6.5 × 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma. This is the seventh case described in the literature. Multiple foci of high-grade dysplasia/carcinoma in situ were found with a microscopic focus of invasive carcinoma in review of the pathology, making this only the second case reporting malignant transformation. It is presented to illustrate the premalignant potential in a biliary epithelial tumor currently categorized as benign.http://dx.doi.org/10.1155/2012/793963 |
| spellingShingle | N. Thao T. Nguyen Theresa R. Harring Laurie Holley John A. Goss Christine A. O’Mahony Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report Case Reports in Hepatology |
| title | Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report |
| title_full | Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report |
| title_fullStr | Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report |
| title_full_unstemmed | Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report |
| title_short | Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report |
| title_sort | biliary adenofibroma with carcinoma in situ a rare case report |
| url | http://dx.doi.org/10.1155/2012/793963 |
| work_keys_str_mv | AT nthaotnguyen biliaryadenofibromawithcarcinomainsituararecasereport AT theresarharring biliaryadenofibromawithcarcinomainsituararecasereport AT laurieholley biliaryadenofibromawithcarcinomainsituararecasereport AT johnagoss biliaryadenofibromawithcarcinomainsituararecasereport AT christineaomahony biliaryadenofibromawithcarcinomainsituararecasereport |