UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases

UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases

In this study, we present a comprehensive pipeline to train and compare a broad spectrum of machine learning and deep learning brain clocks, integrating diverse preprocessing strategies and correction terms. Our analysis also includes established methodologies which have shown success in prior UK Bi...

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Bibliographic Details
Main Authors: Marco Capó, Silvia Vitali, Georgios Athanasiou, Nicole Cusimano, Daniel García, Garth Cruickshank, Bipin Patel
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:NeuroImage
Subjects:
Brain age prediction
Neurodegenerative condition diagnosis
UK Biobank
Machine learning
T1 weighted MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811925000667
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http://www.sciencedirect.com/science/article/pii/S1053811925000667

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