Exploring the efficacy of Benincasa hispida extract on obesity linked inflammatory bowel disease by integrating computational analysis and experimental validations

Exploring the efficacy of Benincasa hispida extract on obesity linked inflammatory bowel disease by integrating computational analysis and experimental validations

Abstract The association of obesity with inflammatory bowel disease (IBD) can be understood by the intricate role of pro- and anti-inflammatory cytokines, especially adipokines, which are secreted by adipose tissue and are responsible for IBD because of their structural similarity with tumor necrosi...

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Main Authors: Santosh B. Patil, Manisha B. Kuvalekar, Deepak A. Yaraguppi, D. S. N. B. K. Prasanth, Sangameshwar G. Halkavatagi, Gururaj B. Tennalli, Mukhatar Ahmed Javali, T. M. Yunus Khan
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Obesity
IBD
Benincasa hispida
Network pharmacology
Molecular Docking
Molecular dynamics
Online Access:https://doi.org/10.1038/s41598-025-99256-6
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https://doi.org/10.1038/s41598-025-99256-6

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