Associations between a polymorphism in the pleiotropic GCKR and Age-related phenotypes: the HALCyon programme.

Associations between a polymorphism in the pleiotropic GCKR and Age-related phenotypes: the HALCyon programme.

<h4>Background</h4>The glucokinase regulatory protein encoded by GCKR plays an important role in glucose metabolism and a single nucleotide polymorphism (SNP) rs1260326 (P446L) in the gene has been associated with several age-related biomarkers, including triglycerides, glucose, insulin...

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Main Authors: Tamuno Alfred, Yoav Ben-Shlomo, Rachel Cooper, Rebecca Hardy, Ian J Deary, Jane Elliott, Sarah E Harris, Mika Kivimaki, Meena Kumari, Chris Power, John M Starr, Diana Kuh, Ian N M Day, HALCyon study team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0070045
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https://doi.org/10.1371/journal.pone.0070045

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