Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets

Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets

ABSTRACT Cancer progression is often driven by aberrant cell growth and genetic mutations, leading to metastasis. The transforming growth factor‐beta (TGF‐β) pathway, a key regulator of cellular growth and differentiation, exhibits dual roles in cancer by initially acting as a tumor suppressor and l...

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Main Authors: Reham Hassan Mekky, Mohammed E. Abo‐El Fetoh, Safaa A. Faheem, Abdullah F. Radwan, Mariam H. Fawzy, Aya M. Mustafa, Mohamed A. Said, Daniela Calina, Javad Sharifi‐Rad, William C. Cho
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:MedComm
Subjects:
angiogenesis
apoptosis
cancer progression
natural compounds
TGF‐β pathway
therapeutic modulation
Online Access:https://doi.org/10.1002/mco2.70278
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https://doi.org/10.1002/mco2.70278

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