The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway

The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway

Melanoma is among the most abundant malignancies in the US and worldwide. Ligstroside aglycone (LA) is a rare extra-virgin olive oil-derived monophenolic secoiridoid with diverse bioactivities. LA dose–response screening at the NCI 60 cancer cells panel identified the high sensitivity of the Malme-3...

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Bibliographic Details
Main Authors: Md Ashiq Mahmud, Abu Bakar Siddique, Afsana Tajmim, Judy Ann King, Khalid A. El Sayed
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
<i>BRAF V600E</i> mutation
ELOVL6
GPD1
ligstroside aglycone
melanoma
olive phenolics
Online Access:https://www.mdpi.com/1420-3049/30/1/139
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