CRISPR/Cas-mediated mRNA knockdown in the embryos of Xenopus tropicalis

CRISPR/Cas-mediated mRNA knockdown in the embryos of Xenopus tropicalis

Abstract The Xenopus tropicalis (Western clawed frog) is an important amphibian model for genetics, developmental and regenerative biology, due to its diploid genetic background and short generation time. CRISPR-Cas13 and CRISPR interference (CRISPRi) systems have recently been employed to suppress...

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Main Authors: Xiao-Lin Lin, Yi-Min Zhou, Ke Meng, Jia-Yi Yang, Han Zhang, Jin-Hua Lin, Hai-Yan Wu, Xiao-Yu Wang, Hui Zhao, Shan-Shan Feng, Kyu-Sang Park, Dong-Qing Cai, Li Zheng, Xu-Feng Qi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell & Bioscience
Subjects:
Cas13
CRISPRi
Knockdown
Xenopus tropicalis
Online Access:https://doi.org/10.1186/s13578-025-01397-8
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https://doi.org/10.1186/s13578-025-01397-8

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