Whole-genome sequencing reveals patterns of runs of homozygosity underlying genetic diversity and selection in domestic rabbits

Whole-genome sequencing reveals patterns of runs of homozygosity underlying genetic diversity and selection in domestic rabbits

Abstract Background Runs of homozygosity (ROH) are continuous segments of homozygous genotypes inherited from both parental lineages. These segments arise due to the transmission of identical haplotypes. The genome-wide patterns and hotspot regions of ROH provide valuable insights into genetic diver...

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Bibliographic Details
Main Authors: Xinxin Ping, Yuan Chen, Hui Wang, Zhuoya Jin, Qianting Duan, Zhanjun Ren, Xianggui Dong
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Genomics
Subjects:
Rabbit
Runs of homozygosity
Inbreeding
Genome resequencing
ROH island
Online Access:https://doi.org/10.1186/s12864-025-11616-8
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