Application of CIBERSORTx and BayesPrism to deconvolution of bulk RNA-seq data from human myocardium and skeletal muscle

Application of CIBERSORTx and BayesPrism to deconvolution of bulk RNA-seq data from human myocardium and skeletal muscle

RNA-sequencing (RNA-seq) is an important tool to explore molecular mechanisms of disease. Technological advances mean this can be performed at the single-cell level, but the large sample sizes needed in clinical studies are currently prohibitively expensive and complex. Deconvolution of bulk RNA-seq...

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Bibliographic Details
Main Authors: Marcella Conning-Rowland, Chew W. Cheng, Oliver Brown, Marilena Giannoudi, Eylem Levelt, Lee D. Roberts, Kathryn J. Griffin, Richard M. Cubbon
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
RNA-Seq
Deconvolution
Myocardium
Skeletal muscle
Age
Sex
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025008795
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