Transcriptional Responses of In Vitro Blood–Brain Barrier Models to Shear Stress
Endothelial cells throughout the body sense blood flow, eliciting transcriptional and phenotypic responses. The brain endothelium, known as the blood–brain barrier (BBB), possesses unique barrier and transport properties, which are in part regulated by blood flow. We utilized RNA sequencing to analy...
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| Main Authors: | Koji L. Foreman, Benjamin D. Gastfriend, Moriah E. Katt, Sean P. Palecek, Eric V. Shusta |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/15/2/193 |
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