Transcriptional Responses of In Vitro Blood–Brain Barrier Models to Shear Stress

Endothelial cells throughout the body sense blood flow, eliciting transcriptional and phenotypic responses. The brain endothelium, known as the blood–brain barrier (BBB), possesses unique barrier and transport properties, which are in part regulated by blood flow. We utilized RNA sequencing to analy...

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Bibliographic Details
Main Authors: Koji L. Foreman, Benjamin D. Gastfriend, Moriah E. Katt, Sean P. Palecek, Eric V. Shusta
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/15/2/193
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