Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids
1,3-benzodioxole is one prominent biological active moiety which is abundant in numerous natural products. In this work we have synthesized 1,3-benzodioxole based ionic liquids using the different fluorides and have evaluated their anti-bacterial properties on Gram negative (-) Escherichia coli and...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Journal of Ionic Liquids |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772422024000533 |
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| author | Sagar Panchal Hitesh Sehrawat Nisha Yadav Shipra Chandra Vivek Mishra Neera Sharma Ramesh Chandra |
| author_facet | Sagar Panchal Hitesh Sehrawat Nisha Yadav Shipra Chandra Vivek Mishra Neera Sharma Ramesh Chandra |
| author_sort | Sagar Panchal |
| collection | DOAJ |
| description | 1,3-benzodioxole is one prominent biological active moiety which is abundant in numerous natural products. In this work we have synthesized 1,3-benzodioxole based ionic liquids using the different fluorides and have evaluated their anti-bacterial properties on Gram negative (-) Escherichia coli and Gram positive (+) Staphylococcus aureus bacterial strains were assessed. In this report we have reported the MIC (minimum inhibitor concentration) and ZOI (zone of inhibition) analysis of the different combinations and the best combination was the further used for the in-silico computational study for the interaction at the atomic level. |
| format | Article |
| id | doaj-art-23dcce72e54b45e0bcf9f96eab3d6bb0 |
| institution | Kabale University |
| issn | 2772-4220 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Ionic Liquids |
| spelling | doaj-art-23dcce72e54b45e0bcf9f96eab3d6bb02025-01-24T04:46:00ZengElsevierJournal of Ionic Liquids2772-42202025-06-0151100130Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquidsSagar Panchal0Hitesh Sehrawat1Nisha Yadav2Shipra Chandra3Vivek Mishra4Neera Sharma5Ramesh Chandra6Drug Discovery and Development lab, Department of Chemistry, University of Delhi. Delhi 110007, IndiaDrug Discovery and Development lab, Department of Chemistry, University of Delhi. Delhi 110007, India; Maharaja Surajmal Brij University, Bharatpur 321201, Rajasthan, IndiaAmity Institute of Click Chemistry Research and Studies, Amity University, Noida sec. 125, UP, IndiaAssociate Professor, Department of Physiology, Sarojini Naidu Medical College, Agar UP, IndiaAmity Institute of Click Chemistry Research and Studies, Amity University, Noida sec. 125, UP, India; Corresponding author: Amity Institute of Click Chemistry Research and Studies, Amity University, Noida sec‑125, UP, India.Hindu College, University of Delhi, Delhi 110007, India; Corresponding author: Department of Chemistry, Hindu College, University of Delhi, Delhi-110007, India.Drug Discovery and Development lab, Department of Chemistry, University of Delhi. Delhi 110007, India; Maharaja Surajmal Brij University, Bharatpur 321201, Rajasthan, India; Dr B.R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi 110007, India; Institute of Nanomedical Sciences, University of Delhi, Delhi 110007, India; Corresponding author: Drug Discovery & Development Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India.1,3-benzodioxole is one prominent biological active moiety which is abundant in numerous natural products. In this work we have synthesized 1,3-benzodioxole based ionic liquids using the different fluorides and have evaluated their anti-bacterial properties on Gram negative (-) Escherichia coli and Gram positive (+) Staphylococcus aureus bacterial strains were assessed. In this report we have reported the MIC (minimum inhibitor concentration) and ZOI (zone of inhibition) analysis of the different combinations and the best combination was the further used for the in-silico computational study for the interaction at the atomic level.http://www.sciencedirect.com/science/article/pii/S27724220240005331,3-benzodioxolImidazolePyridineAnti-bacterialIonic liquids |
| spellingShingle | Sagar Panchal Hitesh Sehrawat Nisha Yadav Shipra Chandra Vivek Mishra Neera Sharma Ramesh Chandra Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids Journal of Ionic Liquids 1,3-benzodioxol Imidazole Pyridine Anti-bacterial Ionic liquids |
| title | Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids |
| title_full | Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids |
| title_fullStr | Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids |
| title_full_unstemmed | Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids |
| title_short | Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids |
| title_sort | anti bacterial evaluation of 1 3 benzodioxole derived imidazolium and pyridinium based ionic liquids |
| topic | 1,3-benzodioxol Imidazole Pyridine Anti-bacterial Ionic liquids |
| url | http://www.sciencedirect.com/science/article/pii/S2772422024000533 |
| work_keys_str_mv | AT sagarpanchal antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids AT hiteshsehrawat antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids AT nishayadav antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids AT shiprachandra antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids AT vivekmishra antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids AT neerasharma antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids AT rameshchandra antibacterialevaluationof13benzodioxolederivedimidazoliumandpyridiniumbasedionicliquids |