The Influence of PK/PD on the Structure of Optimal Controls in Cancer Chemotherapy Models
Mathematical models for cancer chemotherapy as optimal control problems are considered. Results on scheduling optimal therapies when the controls represent the effectiveness of chemotherapeutic agents, or, equivalently, when the simplifying assumption is made that drugs act instantaneously, are comp...
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Main Authors: | Urszula Ledzewicz, Heinz Schättler |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2005-07-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.561 |
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