The Influence of PK/PD on the Structure of Optimal Controls in Cancer Chemotherapy Models

Mathematical models for cancer chemotherapy as optimal control problems are considered. Results on scheduling optimal therapies when the controls represent the effectiveness of chemotherapeutic agents, or, equivalently, when the simplifying assumption is made that drugs act instantaneously, are comp...

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Bibliographic Details
Main Authors: Urszula Ledzewicz, Heinz Schättler
Format: Article
Language:English
Published: AIMS Press 2005-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.561
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