Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals
Background. Conditioned pain modulation (CPM), a phenomenon also known as diffuse noxious inhibitory control, is thought to be affected by various factors, including sex and level of physical activity. However, the involvement of these factors in CPM remains unclear. Methods. Eighty-six healthy youn...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2017/9059140 |
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| author | Yukiko Shiro Tatsunori Ikemoto Yuta Terasawa Young-Chang P. Arai Kazuhiro Hayashi Takahiro Ushida Takako Matsubara |
| author_facet | Yukiko Shiro Tatsunori Ikemoto Yuta Terasawa Young-Chang P. Arai Kazuhiro Hayashi Takahiro Ushida Takako Matsubara |
| author_sort | Yukiko Shiro |
| collection | DOAJ |
| description | Background. Conditioned pain modulation (CPM), a phenomenon also known as diffuse noxious inhibitory control, is thought to be affected by various factors, including sex and level of physical activity. However, the involvement of these factors in CPM remains unclear. Methods. Eighty-six healthy young subjects (M/F, 43/43) participated in this study. Participants were assessed on the basis of their mechanical pressure pain threshold (PPT), CPM response, body mass index (BMI), basal metabolic rate (BMR), and duration of moderate-to-vigorous physical activity (MVPA) over a week, using a motion counter. Response to CPM was evaluated as PPT during painful cold stimulation relative to baseline PPT. Results. Men showed significantly higher baseline PPT than women; however, this difference was no longer significant after controlling for confounders. Stepwise multiple linear regression analyses revealed BMR to be a significant contributor towards baseline PPT in the entire study population. In contrast, although there were no significant contributors to CPM response among men and in the overall study group, MVPA was positively associated with CPM response among women (β = 0.397). Conclusions. These results suggest that, among healthy young individuals, CPM response may be associated with moderate-to-vigorous physical activity in women but not in men. |
| format | Article |
| id | doaj-art-22c95238bb7946a897c1ee59d3b7cf92 |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-22c95238bb7946a897c1ee59d3b7cf922025-02-03T05:59:09ZengWileyPain Research and Management1203-67651918-15232017-01-01201710.1155/2017/90591409059140Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy IndividualsYukiko Shiro0Tatsunori Ikemoto1Yuta Terasawa2Young-Chang P. Arai3Kazuhiro Hayashi4Takahiro Ushida5Takako Matsubara6Department of Physical Therapy, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, JapanMultidisciplinary Pain Center, Aichi Medical University, Aichi, JapanNational Hospital Organization, Higashi Nagoya National Hospital, Aichi, JapanMultidisciplinary Pain Center, Aichi Medical University, Aichi, JapanMultidisciplinary Pain Center, Aichi Medical University, Aichi, JapanMultidisciplinary Pain Center, Aichi Medical University, Aichi, JapanMultidisciplinary Pain Center, Aichi Medical University, Aichi, JapanBackground. Conditioned pain modulation (CPM), a phenomenon also known as diffuse noxious inhibitory control, is thought to be affected by various factors, including sex and level of physical activity. However, the involvement of these factors in CPM remains unclear. Methods. Eighty-six healthy young subjects (M/F, 43/43) participated in this study. Participants were assessed on the basis of their mechanical pressure pain threshold (PPT), CPM response, body mass index (BMI), basal metabolic rate (BMR), and duration of moderate-to-vigorous physical activity (MVPA) over a week, using a motion counter. Response to CPM was evaluated as PPT during painful cold stimulation relative to baseline PPT. Results. Men showed significantly higher baseline PPT than women; however, this difference was no longer significant after controlling for confounders. Stepwise multiple linear regression analyses revealed BMR to be a significant contributor towards baseline PPT in the entire study population. In contrast, although there were no significant contributors to CPM response among men and in the overall study group, MVPA was positively associated with CPM response among women (β = 0.397). Conclusions. These results suggest that, among healthy young individuals, CPM response may be associated with moderate-to-vigorous physical activity in women but not in men.http://dx.doi.org/10.1155/2017/9059140 |
| spellingShingle | Yukiko Shiro Tatsunori Ikemoto Yuta Terasawa Young-Chang P. Arai Kazuhiro Hayashi Takahiro Ushida Takako Matsubara Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals Pain Research and Management |
| title | Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals |
| title_full | Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals |
| title_fullStr | Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals |
| title_full_unstemmed | Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals |
| title_short | Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals |
| title_sort | physical activity may be associated with conditioned pain modulation in women but not men among healthy individuals |
| url | http://dx.doi.org/10.1155/2017/9059140 |
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