Patient‐Derived Bladder Cancer Organoids as a Valuable Tool for Understanding Tumor Biology and Developing Personalized Treatment

Patient‐Derived Bladder Cancer Organoids as a Valuable Tool for Understanding Tumor Biology and Developing Personalized Treatment

Abstract Bladder cancer (BC) is a heterogeneous disease with high recurrence rates and variable treatment responses. To address these clinical challenges, the world's first bladder cancer patient‐derived organoids (PDOs) biobank is established based on an Asian population. Thirty‐six BC‐PDOs ar...

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Main Authors: Hongda Zhao, Na Lin, Vincy Wing Sze Ho, Kang Liu, Xuan Chen, Hongwei Wu, Peter Ka‐Fung Chiu, Linda Huang, Zahra Dantes, Ka‐Leung Wong, Ho‐Fai Chau, Ivan Ching‐Ho Ko, Chris Ho‐Ming Wong, David Ka‐Wai Leung, Steffi Kar‐Kei Yuen, Dinglan Wu, Xiaofan Ding, Chi Fai Ng, Jeremy Yuen‐Chun Teoh
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
bladder cancer
drug screening
organoids
personalized medicine
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202414558
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https://doi.org/10.1002/advs.202414558

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