Recurrent design patterns in the feedback regulation of the mammalian signalling network
Abstract Biochemical networks are characterized by recurrent patterns and motifs, but the design principles underlying the dynamics of the mammalian intracellular signalling network remain unclear. We systematically analysed decay rates of 134 signalling proteins and investigated their gene expressi...
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| Main Authors: | Stefan Legewie, Hanspeter Herzel, Hans V Westerhoff, Nils Blüthgen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2008-05-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2008.29 |
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