Electrochemical Behavior of Biologically Important Indole Derivatives
Voltammetric techniques are most suitable to investigate the redox properties of a new drug. Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. The indole nucleus is an essential ele...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Electrochemistry |
| Online Access: | http://dx.doi.org/10.4061/2011/154804 |
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| _version_ | 1832548382804017152 |
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| author | Cigdem Karaaslan Sibel Suzen |
| author_facet | Cigdem Karaaslan Sibel Suzen |
| author_sort | Cigdem Karaaslan |
| collection | DOAJ |
| description | Voltammetric techniques are most suitable to investigate the redox properties of a new drug. Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. The indole nucleus is an essential element of a number of natural and synthetic products with significant biological activity. Indole derivatives are the well-known electroactive compounds that are readily oxidized at carbon-based electrodes, and thus analytical procedures, such as electrochemical detection and voltammetry, have been developed for the determination of biologically important indoles. This paper explains some of the relevant and recent achievements in the electrochemistry processes and parameters mainly related to biologically important indole derivatives in view of drug discovery and analysis. |
| format | Article |
| id | doaj-art-224ed3e5a54344e3982e3f6eb7951ef6 |
| institution | Kabale University |
| issn | 2090-3537 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Electrochemistry |
| spelling | doaj-art-224ed3e5a54344e3982e3f6eb7951ef62025-02-03T06:14:11ZengWileyInternational Journal of Electrochemistry2090-35372011-01-01201110.4061/2011/154804154804Electrochemical Behavior of Biologically Important Indole DerivativesCigdem Karaaslan0Sibel Suzen1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Tandogan 06100, Ankara, TurkeyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Tandogan 06100, Ankara, TurkeyVoltammetric techniques are most suitable to investigate the redox properties of a new drug. Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. The indole nucleus is an essential element of a number of natural and synthetic products with significant biological activity. Indole derivatives are the well-known electroactive compounds that are readily oxidized at carbon-based electrodes, and thus analytical procedures, such as electrochemical detection and voltammetry, have been developed for the determination of biologically important indoles. This paper explains some of the relevant and recent achievements in the electrochemistry processes and parameters mainly related to biologically important indole derivatives in view of drug discovery and analysis.http://dx.doi.org/10.4061/2011/154804 |
| spellingShingle | Cigdem Karaaslan Sibel Suzen Electrochemical Behavior of Biologically Important Indole Derivatives International Journal of Electrochemistry |
| title | Electrochemical Behavior of Biologically Important Indole Derivatives |
| title_full | Electrochemical Behavior of Biologically Important Indole Derivatives |
| title_fullStr | Electrochemical Behavior of Biologically Important Indole Derivatives |
| title_full_unstemmed | Electrochemical Behavior of Biologically Important Indole Derivatives |
| title_short | Electrochemical Behavior of Biologically Important Indole Derivatives |
| title_sort | electrochemical behavior of biologically important indole derivatives |
| url | http://dx.doi.org/10.4061/2011/154804 |
| work_keys_str_mv | AT cigdemkaraaslan electrochemicalbehaviorofbiologicallyimportantindolederivatives AT sibelsuzen electrochemicalbehaviorofbiologicallyimportantindolederivatives |