Cloning, expression, and purification of fusion antigens MPT83 and ESAT6 from the local strain of Mycobacterium tuberculosis in Escherichia coli as a seed vaccine candidate against tuberculosis

Cloning, expression, and purification of fusion antigens MPT83 and ESAT6 from the local strain of Mycobacterium tuberculosis in Escherichia coli as a seed vaccine candidate against tuberculosis

Eradicating tuberculosis (TB) globally is increasingly challenging with the growing number of drug-resistant Mycobacterium tuberculosis (M. tuberculosis) strains. The development of more potent TB vaccines is critical to complement overall TB control strategies and overcome the growing challenge of...

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Main Authors: Rusdina Bte Ladju, Ahyar Ahmad, Abdul Karim, Rugaiyah Arfah, Rosana Agus, Najdah Hidayah, Muhammad Nasrum Massi, Astutiati Nurhasanah, Harningsih Karim, Irda Handayani
Format: Article
Language:English
Published: Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology 2025-03-01
Series:Journal of Advanced Biotechnology and Experimental Therapeutics
Subjects:
cloning
mpt83 plus esat6
tuberculosis
vaccine
Online Access:https://www.bsmiab.org/jabet/?mno=202073
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