Whole exome sequencing-based homologous recombination deficiency test for epithelial ovarian cancer

Whole exome sequencing-based homologous recombination deficiency test for epithelial ovarian cancer

Abstract Background The homologous recombination deficiency (HRD) test is an important tool for identifying patients with epithelial ovarian cancer (EOC) benefit from the treatment with poly(adenosine diphosphate-ribose) polymerase inhibitor (PARPi). Using whole exome sequencing (WES)-based platform...

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Bibliographic Details
Main Authors: Ying-Cheng Chiang, Hsien-Neng Huang, Kuan-Ting Kuo, Wuh-Liang Hwu, Po-Han Lin
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian cancer
Homologous recombination deficiency test
Whole-exome sequencing
scarHRD
Online Access:https://doi.org/10.1186/s13048-024-01565-3
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