Mitigation of the effect of variability in digital PCR assays through use of duplexed reference assays for normalization

Digital PCR has been promoted as a technique for obtaining absolute measures of the amount of nucleic acid target sequence in a sample, but still lacks standardization in data reporting. The initial method of representing data as copies per microliter produced inconsistent results and made inter-ass...

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Bibliographic Details
Main Author: Sherry J Coulter
Format: Article
Language:English
Published: Taylor & Francis Group 2018-08-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/btn-2018-0058
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