Identification of pancreatic cancer-specific protease substrates for protease-dependent targeted delivery

Abstract Pancreatic ductal adenocarcinoma (PDAC) presents significant challenges due to the inadequacy of existing chemotherapeutics, which often result in toxicity-dependent dose limitations and premature cessation of therapy. Targeted delivery of therapeutic molecules offers a promising solution....

Full description

Saved in:
Bibliographic Details
Main Authors: Etienne J. Slapak, Danny A. Zwijnenburg, Jan Koster, Maarten F. Bijlsma, C. Arnold Spek
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-024-00542-1
Tags: Add Tag
No Tags, Be the first to tag this record!