In Silico Targeting and Immunological Profiling of PpiA in <i>Mycobacterium tuberculosis</i>: A Computational Approach

In Silico Targeting and Immunological Profiling of PpiA in <i>Mycobacterium tuberculosis</i>: A Computational Approach

Tuberculosis (TB) remains a leading cause of mortality, with drug resistance highlighting the need for new vaccine targets. Peptidyl-prolyl isomerase A (PpiA), a conserved Mycobacterium tuberculosis (Mtb) protein, plays a role in bacterial stress adaptation and immune evasion, making it a potential...

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Bibliographic Details
Main Authors: Mohammad J. Nasiri, Lily Rogowski, Vishwanath Venketaraman
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pathogens
Subjects:
tuberculosis vaccine
peptidyl-prolyl isomerase A (PpiA)
immunoinformatic
epitope prediction
B-cell epitopes
T-cell epitopes
Online Access:https://www.mdpi.com/2076-0817/14/4/370
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