Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study
Objective: The study aimed to explore the potential benefits of vitamin D supplementation in improving acne severity. Methods: This pilot study was carried out at HIT Hospital, Taxila. The study included nine female patients aged between 12 and 30 years, with acne vulgaris and having deficient se...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Rawalpindi Medical University
2023-12-01
|
| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/2364 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Objective: The study aimed to explore the potential benefits of vitamin D supplementation in improving acne severity.
Methods: This pilot study was carried out at HIT Hospital, Taxila. The study included nine female patients aged between 12 and 30 years, with acne vulgaris and having deficient serum 25-hydroxyvitamin D3 (25(OH)D) levels (<30 nmol/L). Exclusion criteria included the use of topical or oral treatments for acne, including retinoids, as well as those with a history of multivitamin or systemic steroid intake, and patients with any chronic disease. Global Acne Grading (GAG) score was used to assess the severity of acne vulgaris. Patients received a daily dosage of 1000 IU of vitamin D drops per day for 2 months so that vitamin D deficiency is corrected. After 2 months, the GAG score was re-calculated and documented. Data analysis was performed using SPSS version 28.
Results: The mean age of the study participants was 18.33 years (SD= 3.3 Years). A statistically insignificant association (p=0.49) and weak positive correlation (r= 0.17, p=0.65) were observed between Vit D levels and acne Status and GAG-1 score on applying chi-square test and Pearson correlation respectively. A paired-sample t-test showed a significant difference in the GAG-1 Score (Mean=25.44, SD=7.6) and GAG-2 Score (M=15.1, SD=4.5) after Vit D supplementation. t (5.3), (p= 0.001).
Conclusion: The results suggest that correcting vitamin D deficiency through supplementation resulted in a significant improvement in acne severity.
Keywords: Acne vulgaris, Vitamin D, GAG score
|
|---|---|
| ISSN: | 1683-3562 1683-3570 |